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Which topical treatment can help reduce hypertrophic granulation tissue?
Calamine lotion
Silver sulfadiazine
Triamcinolone
Antifungal cream
The correct answer is: Triamcinolone
Triamcinolone is particularly effective in the management of hypertrophic granulation tissue due to its potent anti-inflammatory properties. This medication is a corticosteroid that works by reducing inflammation and inhibiting the excessive proliferation of fibroblasts and collagen synthesis, which are key factors in the formation of hypertrophic tissue. By applying triamcinolone topically or through intralesional injection, it can specifically target and diminish the raised and discolored tissue that characterizes hypertrophic granulation. This makes it a preferred option for treating this type of abnormal scarring, promoting more normal healing. In contrast, calamine lotion is primarily used for its soothing effects on irritated skin and does not have the properties necessary to treat hypertrophic granulation tissue. Silver sulfadiazine is mainly utilized for burn wounds to prevent infection and promote healing but does not have a direct mechanism to address the overabundance of granulation tissue. Antifungal creams are designed to treat fungal infections and would not be effective in addressing the underlying issues related to hypertrophic granulation. Thus, the specific action of triamcinolone in reducing inflammation and controlling tissue proliferation makes it the most suitable choice for this condition.