Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

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What initiates the hemostasis process in wound healing?

Collagen interaction with blood
Vasodilation of blood vessels
Neutrophil migration
Formation of new skin cells

The correct answer is: Collagen interaction with blood

The initiation of the hemostasis process in wound healing begins with collagen interaction with blood. When a blood vessel is damaged, collagen fibers are exposed to the bloodstream. Platelets are attracted to this exposure and begin to aggregate, leading to the formation of a platelet plug. Collagen plays a crucial role as it not only serves as a scaffold that platelets adhere to but also activates the clotting cascade, promoting further aggregation and clot formation. This process is vital in the overall wound healing process, as it helps to prevent excessive blood loss and also sets the stage for subsequent phases of healing, including inflammation and tissue repair. The other processes mentioned, such as vasodilation, neutrophil migration, and formation of new skin cells, occur after the hemostasis phase has been initiated and are part of the later stages of wound healing. They play important roles in the inflammatory response and tissue regeneration, but they do not initiate hemostasis itself.